Based on hospital information system data, analysis of effects of different doses of shenmai injection on renal function / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3060-3067, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-238556
ABSTRACT
<p><b>OBJECTIVE</b>To assess whether the dosage of Shenmai injection influences renal function.</p><p><b>METHOD</b>Analysis of hospital information system (HIS) data from 18 national hospitals using Shenmai injections. Patients were aged between 18 to 80 years old. Blood analysis of creatinine and serum urea nitrogen was undertaken 7 days before and after exceeding the maximum recommended dose of 100 mL of Shenmai injection. Propensity score method was used to compare the differences between the two groups of renal function scores.</p><p><b>RESULT</b>The differences in abnormal changes in creatinine and serum urea nitrogen levels between the groups before and after exceeding the recommended dose was not statistically significant, but abnormal changes were detected.</p><p><b>CONCLUSION</b>Based on the available data we did not find that exceeding the recommended dose of Shenmai injection had a significantly deleterious effect on renal function. However, caution should be applied in its clinical use.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Urea
/
Blood
/
Blood Urea Nitrogen
/
Drugs, Chinese Herbal
/
Case-Control Studies
/
Retrospective Studies
/
Hospital Information Systems
/
Creatinine
/
Drug Dosage Calculations
/
Propensity Score
Type of study:
Observational study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS