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Discussion about relativity between post-marketed safety outcome and treatment course of traditional Chinese medicine drugs on basis of reinforced urn processes / 中国中药杂志
Article in Chinese | WPRIM | ID: wpr-238570
Responsible library: WPRO
ABSTRACT
Based on relevant research and development, the possibility of applying the reinforced urn processes (RUPs) statistical approach to traditional Chinese medicine(TCM) drugs safety research is discussed in this paper, primarily through theoretical discussion and simulations. Also introduced are work flows and the key points for the application of the RUPs approach. This potentially new approach has recently been applied to the target estimation of phase I human tolerance clinical trials. A traditional RUPs approach has also been widely applied in the precise point-estimation of allowable longest treatment courses, according to the particular safety outcomes of post-marketed TCM.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Product Surveillance, Postmarketing / Humans / Drugs, Chinese Herbal / Regression Analysis / Treatment Outcome / Drug Therapy Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Product Surveillance, Postmarketing / Humans / Drugs, Chinese Herbal / Regression Analysis / Treatment Outcome / Drug Therapy Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2013 Type: Article