Analysis of rational clinical uses of traditional Chinese medicine injections and factors influencing adverse drug reactions / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2969-2973, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-238573
ABSTRACT
<p><b>OBJECTIVE</b>To rationalize the clinical use and safety are some of the key issues in the surveillance of traditional Chinese medicine injections (TCMIs).</p><p><b>METHOD</b>In this 2011 study, 240 medical records of patients who had been discharged following treatment with TCMIs between 1 and 12 month previously were randomly selected from hospital records. Consistency between clinical use and the description of TCMIs was evaluated. Research on drug use and adverse drug reactions/events using logistic regression analysis was carried out.</p><p><b>RESULT</b>There was poor consistency between clinical use and best practice advised in manuals on TCMIs. Over-dosage and overly concentrated administration of TCMIs occurred, with the outcome of modifying properties of the blood. Logistic regression analysis showed that, drug concentration was a valid predictor for both adverse drug reactions/events and benefits associated with TCMIs.</p><p><b>CONCLUSION</b>Surveillance of rational clinical use and safety of TCMIs finds that clinical use should be consistent with technical drug manual specifications, and drug use should draw on multi-layered logistic regression analysis research to help avoid adverse drug reactions/events.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Logistic Models
/
China
/
Epidemiology
/
Retrospective Studies
/
Clinical Trials as Topic
/
Drug-Related Side Effects and Adverse Reactions
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article
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