Distribution of lymphomas subtypes in Jiangsu Province: a multicenter analysis of 5 147 cases / 中华血液学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the epidemiological characteristics of lymphoma in Jiangsu province.</p><p><b>METHODS</b>A total of 5 147 consecutive lymphoma samples collected from 18 hospitals in Jiangsu province from January 2007 to December 2013 and diagnosed according to the WHO classification were enrolled in this study. Basic epidemiological information including age, gender and lymphoma subtypes was analyzed.</p><p><b>RESULTS</b>The median age of all lymphoma cases was 59(2-96) years, and gender ratio (M/F) was 1.61. The subtypes distribution analysis revealed that Hodgkin lymphoma (HL) accounted for 5.19% (n=241), whereas non-Hodgkin's lymphoma (NHL) accounted for 94.81% (n=4 400). Further analysis displayed B-NHL formed 75.44% (n=3 501) of all cases and T/NK-NHL 16.51% (n=766), diffuse large B-cell lymphoma and NK/T-cell lymphoma were the major subtypes of B-NHL and T/NK-NHL (53.50%, 1 873/3 501 and 31.85%, 244/766), respectively.</p><p><b>CONCLUSION</b>Unique epidemiological characteristics of lymphoma in Jiangsu province was different from other regions in China and western country, which can provide strong theoretical basis for public health, clinical and basic research.</p>