Efficacy and safety of vardenafil in the treatment of erectile dysfunction: a report of 700 cases / 中华男科学杂志
National Journal of Andrology
;
(12): 1092-1096, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-239028
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of long-term on-demand use of vardenafil in the treatment of erectile dysfunction (ED).</p><p><b>METHODS</b>We conducted a questionnaire investigation among 891 ED patients treated by on-demand use of oral vardenafil at 20 mg every 3 days from March 2007 to January 2010, covering the general information of the patients, their need for and attitudes towards the treatment, clinical efficacy and adverse events of the drug, and satisfaction of the patients and their partners after 12 weeks of treatment.</p><p><b>RESULTS</b>Treatment and follow-up were completed in 700 patients, of whom 504 (72%) achieved sufficient hardness and duration of penile erection and overall sexual satisfaction, 84 (12%) admitted to improvement of erectile hardness and duration but not adequate satisfaction, and the other 112 (16%) experienced no significant changes. Significant differences were found in IIEF-5 scores, Rigiscan test results and partners TSS scores before and after the treatment (P < 0.05). Most frequent adverse events included flushing (15%), dizziness and headache (10%), dyspepsia (3%), and nasal congestion (1%).</p><p><b>CONCLUSION</b>Long-term on-demand use of oral vardenafil, in addition to its safety and good tolerance, can effectively improve the erectile function of ED patients, their success rate of sexual intercourse, and overall quality of sexual life.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Piperazines
/
Sulfones
/
Triazines
/
Vasodilator Agents
/
Follow-Up Studies
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
/
Vardenafil Dihydrochloride
/
Imidazoles
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2011
Type:
Article
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