Advance in research on the association of ALDH2 gene polymorphisms with cancer susceptibility in drinkers / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 113-116, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-239522
ABSTRACT
Aldehyde dehydrogenase 2 (ALDH2), as one of the most important alcohol metabolizing enzymes, plays a significant role in the detoxification process of acetaldehyde which is a main carcinogenic product of alcoholic metabolism. Alteration in its genotypes (particularly at the site of rs671) is closely associated with a variety of tumors in drinkers. Recent advance in the research of the association of the ALDH2 gene rs671 polymorphisms with cancer susceptibility in drinkers is reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Alcohol Drinking
/
Genetic Predisposition to Disease
/
Aldehyde Dehydrogenase
/
Aldehyde Dehydrogenase, Mitochondrial
/
Genetics
/
Neoplasms
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2015
Type:
Article
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