Progress on treatment of tendinopathy with platelet-enriched plasma / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 179-186, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-239604
ABSTRACT
Platelet-enriched plasma (PRP) contains high concentration of platelets and abundant growth factors, which is made by centrifuging of blood and separating of blood elements. PRP promotes tendon repair by releasing various cytokines to enhance cell proliferation, tenogenic differentiation, formation and secretion of matrix; meantime, it can reduce pain by inhibiting the expression of pain-associated molecules. A number of clinical studies demonstrated that PRP was effective in treatment of tendinopathy, including patellar tendinopathy, lateral epicondylitis and plantar fasciopathy. However, some studies did not support this conclusion, because of disparity of PRP types, therapeutic courses and injections protocols in clinical application. Based on its safety, PRP can be a choice of treatment for tendinopathy, in case other non-surgical therapies are of no effect.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Blood Platelets
/
Cytokines
/
Cell Biology
/
Intercellular Signaling Peptides and Proteins
/
Tendinopathy
/
Platelet-Rich Plasma
/
Metabolism
Type of study:
Practice guideline
Limits:
Humans
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2016
Type:
Article
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