Transcatheter delivery of recombinant adenovirus vector containing exogenous aquaporin gene in treatment of Sjögren's syndrome / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 86-97, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-239617
ABSTRACT
Sjögren's syndrome is a kind of autoimmune disease, whose main clinical symptoms are dry mouth, dry eye and chronic parotid glandular inflammation. The conservative treatments include artificial tears or saliva,oral administration of corticosteroids,and immunosuppressantsl with limited effectiveness. Along with the development of molecular biology, vast attentions are being paid to researches on gene therapy for Sjögren's syndrome, hopefully to bring gospel to patients with Sjögren's syndrome. This article reviews the recent research progresses on transcatheter delivery of recombinant adenovirus vector with aquaporin gene in experimental treatment of Sjögren's syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autoimmune Diseases
/
Therapeutics
/
Genetic Therapy
/
Sjogren's Syndrome
/
Adenoviridae
/
Aquaporins
/
Catheters
/
Genetic Vectors
/
Genetics
Limits:
Humans
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS