Study on the anticancer activities of the Clematis manshrica saponins in vivo / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1452-1453, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-239647
ABSTRACT
<p><b>OBJECTIVE</b>To study the anticancer activity of the Clematis manshrica saponins in vivo.</p><p><b>METHOD</b>Anticancer activities were tested in mice with experimental tumor (S180, HepA and P388) in vivo.</p><p><b>RESULT</b>The Clematis manshrica saponins showed a significant anticancer activities on Sarcoma-180, HepA and P388 implanted in mice. In S180 sarcoma, the average tumor inhibition rates were 42.78%, 52.06% and 58.25% (P < 0.05-0.01) respectively; The mean inhibition rates were 37.44%, 52.05% and 59.36% (P < 0.05-0.001) in Hep A tumor separately; while in P388 tumor, the mean inhibition rates were 34.50%, 46.78% and 54.39% (P < 0.05-0.01), respectively.</p><p><b>CONCLUSION</b>The results indicate that Clematis manshrica has obvious antitumor effects against various transplanted tumor in mice.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Plants, Medicinal
/
Saponins
/
Sarcoma 180
/
Drugs, Chinese Herbal
/
Leukemia P388
/
Random Allocation
/
Chemistry
/
Plant Roots
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article
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