Study on fingerprint of unfinished product of Nauclea injection / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1156-1158, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-239729
ABSTRACT
<p><b>OBJECTIVE</b>To establish HPLC fingerprints of unfinished product of Nauclea injection.</p><p><b>METHOD</b>A high performance liquid chromatography assay was developed with an Agilent-Extend C18 column, a gradient elutionwater-5% acetonitrile (10 min), 5% acetonitrile-10% acetonitrile (10-60 min), 50% acetonitrile-water (60-70 min), a 0.7 mL x min(-1) flow rate, at detection wavelength, 245 nm within a 70 min total elution time.</p><p><b>RESULT</b>The RSD of relative retention time and peak area of coexist peaks meet to method requirement during the investigation of precision, stability and repeatibity trials. All of the 10 batches of samples share a high similarity.</p><p><b>CONCLUSION</b>This method can be used to control the quality of unfinished product of Nauclea injection.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Quality Control
/
Drugs, Chinese Herbal
/
Chemistry
/
Reproducibility of Results
/
Chromatography, High Pressure Liquid
/
Rubiaceae
/
Injections
/
Methods
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article
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