Comparing the actions of the three flavone ingredients in choerospondias axillaris on arrhythmias induced by aconitine / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1096-1098, 2005.
Article
in Zh
| WPRIM
| ID: wpr-239741
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the actions of the three flavone ingredients in choerospondias axillaris on arrhythmias Induced by aconitine.</p><p><b>METHOD</b>Langendorff perfuse was applied in the experiment, the antiarrhythmic action was to study by using aconitine on the the isolated heart; The antiarrhythmic action of the three flavone ingredients in choerospondias axillaris was to study by using i.v. aconitine in rat to induce arrhythmias.</p><p><b>RESULT</b>Compared with the NS group, sample 1 and sample 2 both significantly prolonged the beginning time of VF of isolated heart and increased the dosage of aconitine, sample 3 reduced the beginning time of VF of isolated heart and decreased the dosage of aconitine, sample 1 and sample 2 both greatly prolonged the beginning time of VE, VT, VF, HA; sample 3 greatly reduced the beginning time of VT,VF. The actions of the three samples were in a concentration-dependent way.</p><p><b>CONCLUSION</b>Sample 1 and sample 2 both resisted the occurrence of arrhythmias induced by aconitine, sample 3 markedly promoted the occurrence of arrhythmias induced by aconitine.</p>
Full text:
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Index:
WPRIM
Main subject:
Plants, Medicinal
/
Arrhythmias, Cardiac
/
Aconitine
/
In Vitro Techniques
/
Random Allocation
/
Chemistry
/
Rats, Wistar
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Anacardiaceae
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Therapeutic Uses
/
Flavones
Limits:
Animals
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article