Scanning electron microscopic study of titanium-hydroxyapatite, the functionally graded-material implanted in rabbits / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>The purpose of this study was to observe the tissue tolerance of Ti-HA functionally graded-material (FGM) and the form of the material-bone interface.</p><p><b>METHODS</b>The sintered Ti -HA FGM, pure HA and pure Ti were respectively implanted into the parietal bone of rabbits. The specimens were observed by SEM at 2, 4, 8 postoperative weeks.</p><p><b>RESULTS</b>In the early stage, the new bone surrounding the Ti -HA FGM formed earlier with larger amount and better maturity than the pure Ti. The condition was similar to the pure HA. Two months after the operation, direct bonding of material-bone interface was formed between the Ti -HA FGM and the new bone as an integral body. However, there was a little space left between the new bone and the pure Ti.</p><p><b>CONCLUSIONS</b>The Ti -HA FGM has good tissue tolerance. Its early integration with bone is similar to pure HA and better than pure Ti.</p>