Investigation of sub-clinical infection of hepatitis E virus in blood donors / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 11-12, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-240526
ABSTRACT
<p><b>OBJECTIVE</b>To understand the prevalence of sub-clinical infection of hepatitis E virus (HEV) among blood donors.</p><p><b>METHODS</b>A cluster sampling strategy was used to sample all blood donors from July to August in 2002 in Beijing. Their blood was tested for IgM and IgG antibody against HEV.</p><p><b>RESULTS</b>The prevalence of anti-HEV IgM among blood donors in Beijing was 1.74%. The rate of abnormal alanine aminotransferase (ALT) in anti-HEV IgM positive donors is significantly higher than anti-HEV IgM negative donors. Among all ALT abnormal donors, 2.68% can be associated with HEV sub-clinical infection. The percentage is similar with HBV but higher than HCV.</p><p><b>CONCLUSION</b>There are sub-clinical infection of HEV among blood donors, which is one of the cause of abnormal ALT in the donors.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Blood Donors
/
Immunoglobulin M
/
Hepatitis Antibodies
/
Epidemiology
/
Hepatitis E virus
/
Hepatitis E
/
Hepacivirus
/
Alanine Transaminase
/
Allergy and Immunology
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hepatology
Year:
2004
Type:
Article
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