Effect of pingchuan mixture on eosinophil cation protein and interleukin-5 in experimental guinea pigs with asthma / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 609-611, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-240908
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Pingchuan Mixture (PCM) on plasma eosinophil cation protein (ECP), interleukin-5 in bronchial alveolar lavage fluid (BALF) and inflammatory cell count in experimental guinea pigs with asthma.</p><p><b>METHODS</b>The eosinophil, neutrophil, lymphocyte count were conducted by conventional method, IL-5 was detected by ELISA and ECP determined by RIA.</p><p><b>RESULTS</b>Levels of eosinophil, neutrophil, lymphocyte, ECP and IL-5 after treatment were significantly lower than those before treatment, the difference between groups treated respectively by PCM, aminophylline, dexamethasone and Dingchuan Zhike Tablet was insignificant.</p><p><b>CONCLUSION</b>PCM could treat asthma by reducing the inflammatory cell count, ECP and IL-5.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Asthma
/
Ribonucleases
/
Bronchoalveolar Lavage Fluid
/
Drugs, Chinese Herbal
/
Blood Proteins
/
Chemistry
/
Ovalbumin
/
Interleukin-5
/
Eosinophil Granule Proteins
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS