Progress on strategies to promote vascularization in bone tissue engineering / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 383-388, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-241033
ABSTRACT
With the continuous development of bone tissue engineering, a variety of emerging bone graft materials provided various methods for repairing bone defects. Early and rapid accomplishment of revascularization of materials interior after implantation of bone transplantation materials is a difficulty faced to bone tissue engineering. Blood vessels ingrowth provides the requisite netritional support for the regeneration reconstruction of bone tissue, for this reason, vascularization plays a significant role in bone tissue engineering. However,there is not a golden standard strategy of vascularization at present. Scaffold materials, cells and growth factors still are three indispensable elements in tissue engineering, and are cardinal points of the promoting vascularization strategies. Multiple growth factors or multiple cells combined with scaffolds, which are hot spots, have obtained excellent vascularization. This review focused on the comprehensive strategies for promoting the successful vascularization of tissue engineered scaffolds.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bone and Bones
/
Neovascularization, Physiologic
/
Tissue Engineering
/
Tissue Scaffolds
/
Methods
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2015
Type:
Article
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