Your browser doesn't support javascript.
loading
Excretion of beta-elemene from rat respiratory tracts / 药学学报
Acta Pharmaceutica Sinica ; (12): 54-56, 2005.
Article in Chinese | WPRIM | ID: wpr-241337
ABSTRACT
<p><b>AIM</b>To investigate the excretion of beta-elemene from the respiratory tracts in male Spraque-Dawley rats.</p><p><b>METHODS</b>After a single administration of beta-elemene to rats at the dosage of 75 mg x kg(-1) (i.v. or i.p.), the exhaled gases were collected and concentrated at various time points. The residues were analyzed by gas chromatography.</p><p><b>RESULTS</b>A minor amount of unchanged beta-elemene was excreted via rat respiratory tracts after iv and ip administration of a single dose. The cumulative excretion were 1.41% and 0.51% respectively.</p><p><b>CONCLUSION</b>The results demonstrated that unchanged beta-elemene excretes from rat respiratory tracts, but may not be the main elimination pathway in rats.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Plants, Medicinal / Respiratory System / Sesquiterpenes / Pharmacokinetics / Chemistry / Chromatography, Gas / Rats, Sprague-Dawley / Curcuma / Infusions, Parenteral / Injections, Intravenous Limits: Animals Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2005 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Plants, Medicinal / Respiratory System / Sesquiterpenes / Pharmacokinetics / Chemistry / Chromatography, Gas / Rats, Sprague-Dawley / Curcuma / Infusions, Parenteral / Injections, Intravenous Limits: Animals Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2005 Type: Article