Relationship between vitamin D and autism spectrum disorder / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 698-702, 2013.
Article
in Zh
| WPRIM
| ID: wpr-241441
Responsible library:
WPRO
ABSTRACT
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder, with multiple genetic and environmental risk factors. The interplay between genetic and environmental factors has become the subject of intensified research in the last several years. Vitamin D deficiency has recently been proposed as a possible environmental risk factor for ASD. Vitamin D has a unique role in brain homeostasis, embryogenesis and neurodevelopment, immunological modulation (including the brain's immune system), antioxidation, antiapoptosis, neural differentiation and gene regulation. Children with ASD had significantly lower serum levels of 25-hydroxy vitamin D than healthy children.Therefore vitamin D deficiency during pregnancy and early childhood may be an environmental trigger for ASD.
Full text:
1
Index:
WPRIM
Main subject:
Physiology
/
Vitamin D
/
Vitamin D Deficiency
/
Child Development Disorders, Pervasive
/
Embryonic Development
/
Genetics
/
Homeostasis
Type of study:
Risk_factors_studies
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2013
Type:
Article