Advance in producing higher alcohols by microbial cell factories / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 1421-1430, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-242469
ABSTRACT
Higher alcohols have a high energy density, low hygroscopicity and can be mixed with gasoline at any ratio. It is the trend to replace fossil fuels with biofuels produced via microbial fermentation of renewable resources. We reviewed the progress in the development of engineered Saccharomyces cerevisiae and Escherichia coli that can produce higher alcohols, as well as the related technology platforms. We mainly focused on the construction of CoA-dependent pathways and alpha-keto acid mediated non-fermentative pathways, analyzed their respective characteristics, and summarized the construction strategies. The problems to be solved and future research direction were also discussed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Saccharomyces cerevisiae
/
Industrial Microbiology
/
Alcohols
/
Escherichia coli
/
Metabolic Engineering
/
Genetics
/
Metabolism
/
Methods
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2013
Type:
Article
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