Progress in microbial production of succinic acid / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 1386-1397, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-242472
ABSTRACT
Succinic acid is one of the key intermediates in the tricarboxylic acid cycle (TCA)and has huge potentials in biopolymer, food, medicine applications. This article reviews recent research progress in the production of succinic acid by microbial fermentation, including discovery and screening of the succinic-acid-producing microbes, the progress of genetic engineering strategy and metabolic engineering technology for construction of succinic acid-producing strains, and fermentation process control and optimization. Finally, we discussed the limitation of current progress and proposed the future research needs for microbial production of succinic acid.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Industrial Microbiology
/
Actinobacillus
/
Succinic Acid
/
Anaerobiospirillum
/
Fermentation
/
Metabolic Engineering
/
Genetics
/
Metabolism
/
Methods
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2013
Type:
Article
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