Virological and serological surveys for H9N2 subtype of influenza A virus in chickens and men in Shenzhen city / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 319-321, 2002.
Article
in Zh
| WPRIM
| ID: wpr-242621
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To understand the distribution of influenza A H9N2 virus in chickens and men in Shenzhen area.</p><p><b>METHODS</b>Virus isolation was performed in embryonated hen s eggs with routine method. The antibody to H9N2 virus was detected with micro-hemagglutination inhibition (HI) test, then the results were checked by using the neutralization assay in MDCK cells.</p><p><b>RESULTS</b>Totally 27 strains of influenza A H9N2 virus were isolated from chickens in farm markets in Shenzhen, whereas no H9N2 virus was isolated from men. Approximately 26% of human sera with the HI titers > or =20 to H9N2 virus were detected. However only 7% of chicken sera with the HI titers > or =20 to H9N2 virus were detected. Meanwhile the HI titer and (MGT) of antibody to H9N2 virus in human sera increased with age. It was also found that there was a close relationship between HI antibody titer to H9N2 virus in human sera and occupation.</p><p><b>CONCLUSIONS</b>The distribution of influenza A H9N2 virus in chicken and men in Shenzhen was rather wide. The human H9N2 virus infection probably derived from chicken H9N2 virus.</p>
Full text:
1
Index:
WPRIM
Main subject:
Influenza A virus
/
Virology
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Blood
/
Hemagglutination Inhibition Tests
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Seroepidemiologic Studies
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Chickens
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China
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Epidemiology
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Classification
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Allergy and Immunology
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
Zh
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2002
Type:
Article