CRISPR-Cas9 mediated genome editing in Caenorhabditis elegans / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1693-1699, 2017.
Article
in Zh
| WPRIM
| ID: wpr-243679
Responsible library:
WPRO
ABSTRACT
The development of genome editing techniques based on CRISPR (Clustered regularly interspaced short palindromic repeats)-Cas9 system has revolutionized biomedical researches. It can be utilized to edit genome sequence in almost any organisms including Caenorhabditis elegans, one of the most convenient and classic genetic model animals. The application of CRISPR-Cas9 mediated genome editing in C. elegans promotes the functional analysis of gene and proteins under many physiological conditions. In this mini-review, we summarized the development of CRISPR-Cas9-based genome editing in C. elegans.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Biotechnology
Year:
2017
Type:
Article