Association between diastolic dysfunction evaluated by left ventricular flow propagation velocity and outcome in patients with hypertrophic cardiomyopathy / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 983-988, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-244081
ABSTRACT
<p><b>OBJECTIVE</b>Left ventricular diastolic dysfunction is common in cardiovascular diseases. Hypertrophic cardiomyopathy(HCM) is a typical disease with diastolic dysfunction. We analyzed the association between the left ventricular flow propagation velocity (FPV), quantified by color M-mode Doppler and as an indicator for diastolic dysfunction, and clinical outcome in patients with HCM.</p><p><b>METHODS</b>Standard echocardiography including FPV was performed in 43 cases with HCM and 22 control cases without a clear history of heart disease. All eligible cases were followed up to more than 1 year.</p><p><b>RESULTS</b>Hospitalization rate due to emerging atrial fibrillation/flutter was 21%, due to emerging ventricular tachycardia was 16%, due to heart failure was 26%, and due to other events was 14% in HCM patients. FPV [(31.6 ± 11.5) cm/s vs. (68.3 ± 18.3) cm/s, P < 0.01] and FPV/E (0.49 ± 0.20 vs. 1.18 ± 0.41, P < 0.01) were significantly lower in HCM group than in control group. PV/E was an independent predictor for atrial fibrillation/flutter and heart failure, IVST was independent predictor for VT (χ(2) = 5.181, P = 0.0228), LAD (χ(2) = 6.172, P = 0.0130) and FPV/E (χ(2) = 3.932, P = 0.0474) were independent risk factors for total cardiac events.</p><p><b>CONCLUSION</b>The incidence of atrial fibrillation and heart failure were closely related with left ventricular diastolic dysfunction in HCM patients and FPV/E was independent predictor for clinical cardiovascular events.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Atrial Fibrillation
/
Cardiomyopathy, Hypertrophic
/
Diagnostic Imaging
/
Case-Control Studies
/
Incidence
/
Risk Factors
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Ventricular Function, Left
/
Echocardiography, Doppler, Color
/
Heart Failure
/
Heart Ventricles
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Cardiology
Year:
2010
Type:
Article
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