Serologic studies of Xinjiang hemorrhagic fever in Bachu county, 2001 / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the situation of Xinjiang hemorrhagic fever (XHF) in patients who have been diagnosed as XHF by clinical methods and to predict the condition in people who were liable to infection and in the host-animals.</p><p><b>METHODS</b>Sera collected from XHF patients and some peasants under the risk of contracting the disease, followed by checking the specific antibody against XHF with IgG-ELISA and IgM capture ELISA, and XHF viral antigen with antigen capture ELISA. In addition, 80 sheep/goats serums were collected from two places where there were more XHF cases and specific IgG antibody against XHF checked by ELISA method.</p><p><b>RESULTS</b>Positive rate of IgG and IgM antibodies were 39.62% (21/53) and 20.75% (11/53) respectively in the serums of patients; one patient's serum showed XHFV antigen positive by antigen capture ELISA. IgG antibody positive rate for peasants' sera was 21.05% (4/19), but IgM antibody detection showed negative for all sera. In sera from 80 sheep and goats, 70% (56/80) showed IgG positive.</p><p><b>CONCLUSION</b>Results showed that XHF broke out in Bachu county from April to June 2001 while recessive infection of the disease remained serious.</p>