A case-control study on family history of Alzheimer's disease / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 54-56, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-244300
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between Alzheimer's disease and its family history of the patients.</p><p><b>METHODS</b>Stratified analyses and logistic regression analysis were used to examine the association between Alzheimer's disease and its family history exposure in 127 cases and 254 matched controls from a population-based case-control study.</p><p><b>RESULTS</b>The risk of Alzheimer's disease was significantly higher in those who had at least one first-degree relative with dementia or major psychosis as compared to those who had no dementia or major relatives with psychosis (OR = 6.25; 8.33). Adjusted for age and level of education, family history of dementia was still associated with Alzheimer's disease positively (OR = 2.07).</p><p><b>CONCLUSION</b>This study provides evidence that familial aggregation of Alzheimer's disease might exist among people living Beijing.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psychotic Disorders
/
Case-Control Studies
/
China
/
Family Health
/
Dementia
/
Alzheimer Disease
/
Genetics
Type of study:
Observational study
/
Risk factors
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2002
Type:
Article
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