The distribution of serum homocysteine and its associated factors in a population of 1 168 subjects in Beijing area / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 32-35, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-244306
ABSTRACT
<p><b>OBJECTIVE</b>To describe serum homocysteine distribution and its associated factors in population of urban and rural areas in Beijing.</p><p><b>METHODS</b>The study population was represented by a randomly selected sample with 1 168 subjects, including both males and females aged 35 - 64. The levels of serum homocycteine were compared and the correlation with other risk factors were analyzed statistically.</p><p><b>RESULTS</b>(1) Geometric mean of serum homocycteine was 15.4 micromol/L in males and 12.2 micromol/L in females (P < 0.001). (2) There was a significant difference in homocysteine levels between urban population and rural population. Men from rural area had 1.5 times higher homocyteine than from urban (18.0 micromol/L vs 12.0 micromol/L, P < 0.001), while the rural women had 1.3 times higher homocysteine level than urban women did. (3) The prevalence rate of hyperhomocysteinemia was 15.3% in population aged 35 - 64 in Beijing area. (4) Gender, residential location (urban or rural), smoking and education had independent effects on level of serum homocysteine by multivariate analysis.</p><p><b>CONCLUSION</b>Population in Beijing had higher serum level and prevalence rate of homocysteine than some western countries. Gender, geographic distribution, smoking and education had some influence on homocysteine level.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
China
/
Sex Factors
/
Rural Health
/
Urban Health
/
Epidemiology
/
Risk Factors
/
Age Factors
/
Hyperhomocysteinemia
/
Homocysteine
Type of study:
Etiology study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2002
Type:
Article
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