Comparative analysis of seven marine biological source of mineral drugs / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3321-3325, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-244572
ABSTRACT
The marine biological source of mineral drugs recorded in Chinese Pharmacopoeia (2010 version) mainly including pearl, nacre, clam shell, common oyster shell, ark shell, cuttle bone, and sea-ear shell are widely used in clinical. Calcium carbonate and a small amount of protein are the main components in this type of drugs. In this paper, a systematical and comparable study were carried out by determination of calcium carbonate by EDTA titration method, the crystal of calcium carbonate by X-Ray powder diffraction and the total amino acids (TAAs) of the hydrolyzed samples by ultraviolet spectrophotometry method. As a result, the crystal structure is calcite for common oyster shell, mixture of calcite and aragonite for nacre and sea-ear shell, aragonite for the other drugs. The content of calcium carbonate ranged from 86% to 96%. Cuttle bone has the highest amount of TAAs among the seven drugs which reached 1.7% while clam shell has the lowest content of 0.16% on average. In conclusion, an effective method was developed for the quality control of marine mineral drugs by comprehensive analysis of calcium carbonate and TAAs in the seven marine mineral drugs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality Control
/
Reference Standards
/
Seawater
/
Species Specificity
/
Spectrophotometry, Ultraviolet
/
X-Ray Diffraction
/
Calcium Carbonate
/
Pharmaceutical Preparations
/
Chemistry
/
Reproducibility of Results
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2014
Type:
Article
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