Clinical epidemiology of gastric cancer
Singapore medical journal
;
: 621-628, 2014.
Article
in English
| WPRIM
| ID: wpr-244766
ABSTRACT
Gastric cancer is the second leading cause of cancer-related mortality and the fourth most common cancer globally. There are, however, distinct differences in incidence rates in different geographic regions. While the incidence rate of gastric cancer has been falling, that of gastric cardia cancers is reportedly on the rise in some regions. Helicobacter pylori (H. pylori) infection is a major risk factor of non-cardia gastric cancer, and data has emerged concerning the role of H. pylori eradication for primary prevention of gastric cancer. Dietary, lifestyle and metabolic factors have also been implicated. Although addressing these other factors may contribute to health, the actual impact in terms of cancer prevention is unclear. Once irreversible histological changes have occurred, endoscopic surveillance would be necessary. A molecular classification system offers hope for molecularly tailored, personalised therapies for gastric cancer, which may improve the prognosis for patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Global Health
/
Epidemiology
/
Incidence
/
Risk Factors
/
Helicobacter pylori
/
Helicobacter Infections
/
Genetics
/
Microbiology
/
Obesity
Type of study:
Etiology study
/
Incidence study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Singapore medical journal
Year:
2014
Type:
Article
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