Progress of the regulation effect of ginsenosides on HPA axis / 药学学报
Acta Pharmaceutica Sinica
; (12): 569-575, 2014.
Article
in Zh
| WPRIM
| ID: wpr-245045
Responsible library:
WPRO
ABSTRACT
Ginseng is a typical adaptogen which has resistance to various stresses. This effect is related to the hypothalamic-pituitary-adrenal (HPA) axis. As the main active ingredients, saponin has the similar structure to steroids. The regulation characteristics of ginseng saponin on the HPA axis are narrated from the aspects of total saponin and saponin monomers in this paper after the introduction of adaptation definition and HPA axis regulation mechanisms. Pharmacological effects of ginseng saponin and the regulation effect of HPA axis are summarized finally.
Full text:
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Index:
WPRIM
Main subject:
Pharmacology
/
Pituitary-Adrenal System
/
Corticosterone
/
Adaptation, Physiological
/
Chemistry
/
Adrenocorticotropic Hormone
/
Bodily Secretions
/
Ginsenosides
/
Panax
/
Hypothalamo-Hypophyseal System
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2014
Type:
Article