Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection / 대한해부학회지
Anatomy & Cell Biology
;
: 331-336, 2011.
Article
in English
| WPRIM
| ID: wpr-24635
ABSTRACT
Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukocyte antigen, class I, G (sHLA-G) antigen is a non-classical class I molecule that has been widely considered as a marker of pregnancy failure or implantation success. In the current study of some Iranian patients, we examined the concentration of sHLA-G at different time points after intracytoplasmic sperm injection and compared the rates to the morphology and quality of the selected embryos. We showed that the concentration of sHLA-G increases over time in high-quality embryos. We conclude that there is a positive relationship between morphology, quality, and sHLA-G concentration. We suggest that this relationship can be used to increase the chance of a successful pregnancy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reproductive Techniques
/
Pregnancy Rate
/
Sperm Injections, Intracytoplasmic
/
Culture Media
/
Reproductive Techniques, Assisted
/
Embryonic Structures
/
HLA-G Antigens
/
Leukocytes
Limits:
Humans
/
Pregnancy
Language:
English
Journal:
Anatomy & Cell Biology
Year:
2011
Type:
Article
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