Genetic analysis of Yersinia pestis strains isolated in China / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 1005-1009, 2003.
Article
in Zh
| WPRIM
| ID: wpr-246416
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>The strains of Yersinia pestis isolated in different period and different natural foci in China were analyzed.</p><p><b>METHODS</b>Traditional and molecular biological methods were used. Rhamnose fermentation, rRNA gene copy number, nitrite reduction, and the glycerol fermentation were important characters for typing, and pulse field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD) profile could reflect the genetic distance between the strains.</p><p><b>RESULTS</b>The strains could be divided into 15 genetic types by those 6 characters with each of them covered an isolated geographical territories.</p><p><b>CONCLUSION</b>The characters of strains were described; the genetic relationship of different types, their evolution, and the forming and shift of plague natural foci were analyzed.</p>
Full text:
1
Index:
WPRIM
Main subject:
Yersinia pestis
/
China
/
Classification
/
Electrophoresis, Gel, Pulsed-Field
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Random Amplified Polymorphic DNA Technique
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Databases, Genetic
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Genetic Drift
/
Genetics
/
Geography
/
Mutation
Country/Region as subject:
Asia
Language:
Zh
Journal:
Chinese Journal of Epidemiology
Year:
2003
Type:
Article