Application of Decision Tree for the Classification of Antimicrobial Peptide
Genomics & Informatics
;
: 121-125, 2004.
Article
in English
| WPRIM
| ID: wpr-24695
ABSTRACT
The purpose of this study was to investigate the use of decision tree for the classification of antimicrobial peptides. The classification was based on the activities of known antimicrobial peptides against common microbes including Escherichia coli and Staphylococcus aureus. A feature selection was employed to select an effective subset of features from available attribute sets.Sequential applications of decision tree with 17 nodes with 9 leaves and 13 nodes with 7 leaves provided the classification rates of 76.74% and 74.66% against E. coli and S. aureus, respectively. Angle subtended by positively charged face and the positive charge commonly gave higher accuracies in both E. coli and S. aureus datasets. In this study, we describe a successful application of decision tree that provides the understanding of the effects of physicochemical characteristics of peptides on bacterial membrane.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptides
/
Staphylococcus aureus
/
Decision Trees
/
Classification
/
Escherichia coli
/
Dataset
/
Membranes
Type of study:
Health economic evaluation
/
Prognostic study
Language:
English
Journal:
Genomics & Informatics
Year:
2004
Type:
Article
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