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Dyslipidemia and outcome in patients with acute ischemic stroke / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences ; (12): 106-110, 2014.
Article in English | WPRIM | ID: wpr-247078
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between dyslipidemia and outcome in patients with acute ischemic stroke.</p><p><b>METHODS</b>Data about 1 568 patients with acute ischemic stroke were collected from 4 hospitals in Shandong Province from January 2006 to December 2008. National Institute of Health Stroke Scale (NIHSS) >10 at discharge or death was defined as the outcome. Effect of dyslipidemia on outcome in patients with acute ischemic stroke was analyzed by multivariate logistic regression analysis and propensity score-adjusted analysis, respectively.</p><p><b>RESULTS</b>The serum levels of TC, LDL-C, and HDL-C were significantly associated with the outcome in patients with acute ischemic stroke. Multivariate logistic regression analysis and propensity score-adjusted analysis showed that the ORs and 95% CIs were 3.013 (1.259, 7.214)/2.655 (1.298, 5.43), 3.157 (1.306, 7.631)/3.405 (1.621, 7.154), and 0.482 (0.245, 0.946)/0.51 (0.282, 0.921), respectively, for patients with acute ischemic stroke. Hosmer-Lemeshow goodness-of-fit test showed no significant difference in observed and predicted risk in patients with acute ischemic stroke (chi-square=8.235, P=0.411).</p><p><b>CONCLUSION</b>Serum levels of TC, LDL-C, and HDL-C are positively related with the outcome in patients with acute ischemic stroke.</p>
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Blood / China / Cholesterol / Epidemiology / Mortality / Brain Infarction / Dyslipidemias Type of study: Prognostic study Limits: Aged / Aged80 / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Blood / China / Cholesterol / Epidemiology / Mortality / Brain Infarction / Dyslipidemias Type of study: Prognostic study Limits: Aged / Aged80 / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2014 Type: Article