Effect of purple sweet potato on lipid metabolism and oxidative stress in hyperlipidemic rats / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 360-364, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-247246
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of purple sweet potato on lipid metabolism and oxidative stress in hyperlipidemic rats.</p><p><b>METHODS</b>Forty male SD rats were randomly divided into 4 groups normal control group, high-fat control group, high purple sweet potato groups, low purple sweet potato group. The rats were fed with different diets for 6w respectively.</p><p><b>RESULTS</b>Serum TC, TG levels were significantly lower in high dosage group than in high-fat control group; while only serum TG was significantly lower in low dosage group than in high-fat control group, these changes started at the third week and lasted to the end of experiment. Serum LDL-C and AI levels were significantly lower in high and low dosage group than in high-fat control group, whereas, serum HDL-C was significantly higher than that in high-fat control group at w3 and lasted to the end of experiment. Serum SOD was significantly higher in high and low dosage group than in high-fat control group, whereas, serum MDA was significantly lower than that in high-fat control group at w6.</p><p><b>CONCLUSION</b>Purple sweet potato can decrease serum lipids and reduce hepatic oxidative stress in hyperlipidemic rats.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Rats, Sprague-Dawley
/
Oxidative Stress
/
Ipomoea batatas
/
Disease Models, Animal
/
Lipid Metabolism
/
Hyperlipidemias
/
Lipids
/
Metabolism
Limits:
Animals
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2011
Type:
Article
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