Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 871-873, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-247370
ABSTRACT
<p><b>OBJECTIVE</b>To develop a HPLC method for the determination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.</p><p><b>METHOD</b>The separation was performed at 30 degrees C on an Eclipse XDB-C18 column (4.6 mm x 150 mm, 5 microm) eluted with the mobile phase consisted of acetonitrile-water(4555). The detection wavelength was 250 nm.</p><p><b>RESULTS</b>The standard curve for evodiamine is linear in the range of 0.0510-0.560 microg, the average recovery was 97.5% (RSD 1.0%). The standard curve for rutacarpine is linear in the range of 0.0508-0.559 microg, the average recovery was 98.7% (RSD 1.5%).</p><p><b>CONCLUSION</b>The method is specific, accurate and stable. It can be used for detemination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality Control
/
Quinazolines
/
Reference Standards
/
Capsules
/
Drugs, Chinese Herbal
/
Linear Models
/
Chemistry
/
Reproducibility of Results
/
Chromatography, High Pressure Liquid
/
Alkaloids
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2011
Type:
Article
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