An epidemiological study on sexual transmission of human immunodeficiency virus among pre-marital group in Yining city, Xinjiang / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 322-324, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-247530
ABSTRACT
<p><b>OBJECTIVE</b>To study the human immunodeficiency virus (HIV) status through heterosexual transmission in Yining city and to provide information on effective intervention measures.</p><p><b>METHODS</b>Cohort of HIV sero-discordant couples identified from 1997 to 2000 was formed. Proportional risk model was used to analyze the time of HIV sero-conversion and the related factors. All the recruiters were under informed consent.</p><p><b>RESULTS</b>Through following on 22 sero-discordant couples, we found that the incidence density (ID) of HIV sero-conversion was 32.49/100 person-year (PY) with 33.74/100 PY for women. In the proportional hazard model, the course of sero-conversion was only 2.43 years and the frequency of sexual contact was statistically significant (>or= 3 times/week vs. < 3 time/week RR = 1.984, 95% CI 1.045 - 3.767), indicating this factor was related to the hazard of HIV sero-conversion. However, the viral load of HIV infections has no such effect on HIV sero-conversion of their spouses. In addition, the ratio of CD4(+)/CD8(+) was lower in spouses of HIV sero-conversion than that in spouses of HIV non-sero conversion (t test t = 4.77, P < 0.01).</p><p><b>CONCLUSION</b>In order to control HIV transmission among general population, we suggested that HIV/AIDS counseling and testing be developed for pre-marital people in the region with high HIV prevalence.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sexual Behavior
/
Enzyme-Linked Immunosorbent Assay
/
Sexually Transmitted Diseases, Viral
/
HIV Infections
/
Proportional Hazards Models
/
China
/
Blotting, Western
/
Epidemiology
/
Incidence
/
HIV
Type of study:
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2004
Type:
Article
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