Comparison of the effectiveness of percutaneous microwave ablation versus hepatectomy for hepatocellular carcinoma / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 301-307, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-248364
ABSTRACT
<p><b>OBJECTIVE</b>To compare the effectiveness of percutaneous microwave ablation ( MWA) versus hepatectomy for multifocal hepatocellular carcinoma.</p><p><b>METHODS</b>From August 2002 to March 2012, one hundred and twenty-two patients with multifocal hepatocellular carcinoma (diameters 1 to 7 cm, 2 to 4 lesions) were treated by either complete MWA or radical hepatectomy, and their clinical data were collected and analyzed.The patients were divided into MWA group (n = 50) and resection group (n = 72), and the resection group was matched by MWA group based on clinical parameters. The survival and complications in the two groups were compared.</p><p><b>RESULTS</b>The overall 1-, 3- and 5-year survival rates were 100.0%, 73.0% and 62.0%, respectively, in the MWA group, and 80.0%, 56.0%, and 41.0%, respectively, in the resection group (P < 0.05). The corresponding recurrence-free survival rates were 88.0%, 63.0%, and 52.0% in the MWA group, and 68.0%, 45.0%, and 36.0%, respectively, in the resection group (P< 0.05). The multivariate Cox regression analysis indicated that albumin level, performance status, treatment modality, and tumor size were independent prognostic factors.</p><p><b>CONCLUSION</b>Compared with hepatectomy, percutaneous microwave ablation is a minimally invasive and reproducible procedure, and can improve the survival in patients with multifocal hepatocellular carcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Radiotherapy
/
General Surgery
/
Genetic Engineering
/
Survival Rate
/
Regression Analysis
/
Mortality
/
Treatment Outcome
/
Catheter Ablation
/
Carcinoma, Hepatocellular
/
Therapeutic Uses
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2015
Type:
Article
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