Y-chromosome-specific microsatellite variation in Li ethnic groups of Hainan Island, China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 46-48, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-248503
ABSTRACT
<p><b>OBJECTIVE</b>The study was conducted to reveal the distribution of genetic polymorphism of four Y chromosome specific short tandem repeat (Y-specific STR) loci in Li ethnic groups in Hainan Island, China.</p><p><b>METHODS</b>Four tetranucleotide STR loci were simultaneously amplified with fluorescently labeled primers, and genotypes were determined with an automated DNA sequencer.</p><p><b>RESULTS</b>Among 230 unrelated males, the alleles at the four Y-specific STR loci were composed of some complex repeat structure. 4,5,4,5 alleles were observed in loci DYS3891, DYS390, DYS391, DYS393 respectively. A set of human allele ladders for the typing of the four Y-specific STRs was obtained in Li ethnic population. Gene diversity index (D) and haplotype diversity data were estimated for the four Y-STRs.</p><p><b>CONCLUSION</b>The preliminary study indicates a reference population for detecting male migration events and should be useful in population genetics and forensic applications.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Genetic Variation
/
Haplotypes
/
DNA
/
Chemistry
/
China
/
Sequence Analysis, DNA
/
Microsatellite Repeats
/
Chromosomes, Human, Y
/
Gene Frequency
/
Genetics
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2003
Type:
Article
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