Variations of hepatitis B virus infection epidemic pattern after long-term HBV vaccine immunization / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 253-255, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-248787
ABSTRACT
<p><b>OBJECTIVE</b>To study the epidemic pattern and trend of HBV infection in the area where the people had been immunized by HBV vaccine for 20 years.</p><p><b>METHODS</b>The whole sampling method was applied in combination with cross-sectional investigation. Blood samples were taken from every member of families. Markers of HBV infection were determined by using solid-phase radioimmunoassay (SPRIA).</p><p><b>RESULTS</b>(1) The average HBsAg positive rate was 7.5%. The positive rate of markers for HBV infection of 0-19 years old subjects were lower than those of > or = 20 years old subjects. (2) The positive rate of HBsAg of 0-19 years old subjects in 1985 was higher than that in 2005. The anti-HBs positive rate in 1985 stemmed to be higher with age. It was 12.4% in 1- age group to 53.8% in >60 years age group. While the result of 2005 showed that the anti-HBs positive rate of 0-19 years old subjects dropped with age. The anti-HBc positive rate in 1985 also tended to be higher with age. But the result of 2005 showed that the rate of 0-19 years old subjects was just 1.4% to 16.8%.</p><p><b>CONCLUSION</b>The epidemic patterns of HBV infection have had significant variations in the target population. HBV vaccine immunization has obtained excellent efficacy.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Blood
/
Seroepidemiologic Studies
/
China
/
Epidemiology
/
Cross-Sectional Studies
/
Immunization
/
Treatment Outcome
/
Hepatitis B Vaccines
/
Therapeutic Uses
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2007
Type:
Article
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