Study on the characteristic of Surveillance Creutzfeldt-Jakob disease patients from January to August in 2006 in China / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 205-207, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-248803
ABSTRACT
<p><b>OBJECTIVE</b>To describe the incidence condition and characteristic of Creutzfeldt-Jakob disease (CJD) in China.</p><p><b>METHODS</b>The clinical and epidemical information of patients from China CJD surveillance network was analyzed. Blood and cerebrospinal fluid (CSF) specimens from these patients were differently collected to be used to detect the 14-3-3 protein in the CSF and to analyze the PRNP gene.</p><p><b>RESULTS</b>Ten possible and 8 probable clinically diagnosed CJD patients were found. These patients had sporadic CJD. There were no geographic clustering and occupational risk with these patients. The mean age at onset of disease was approximately 60 years. The male to female ratio was approximately 11; rapidly progressive dementia was the main early symptom, which was present in 44% of patients.</p><p><b>CONCLUSION</b>The geographic distribution, occupation, the ratio of male to female and the mean age of onset were consistent with the characteristics of sporadic CJD.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prions
/
Cerebrospinal Fluid
/
China
/
Blotting, Western
/
Polymerase Chain Reaction
/
Population Surveillance
/
Epidemiology
/
Creutzfeldt-Jakob Syndrome
/
14-3-3 Proteins
/
Prion Proteins
Type of study:
Screening study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS