Analysis of the result of 409 cases with liver cirrhosis and severe hepatitis by using the model for end-stage liver disease / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To analyze the influence of the model for end-stage liver disease (MELD) results in 409 cases with liver cirrhosis and severe hepatitis and compare with Child-Pugh scoring system.</p><p><b>METHODS</b>The data of 409 patients with liver cirrhosis and severe hepatitis were collected and analyzed by using the Child-Pugh and MELD scoring systems, and Chiss statistical software was applied.</p><p><b>RESULTS</b>There is a statistical significance between either results of MELD of group A, B, C, D; there is a statistical significance between either group in total serum bilirubin and creatinine, but not in INR.</p><p><b>CONCLUSION</b>The changes in total serum bilirubin and creatinine can influence the result significantly, not the INR, and a better way to predict the prognosis of severe liver disease may be application of MELD combined with clinical experience.</p>