Role of Wnt/β-catenin signaling pathway in promoting tumorigenesis of hepatocellular carcinoma / 南方医科大学学报
Journal of Southern Medical University
;
(12): 913-917, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-249333
ABSTRACT
Wnt/β-catenin signaling pathway has a close relationship with cancer and is abnormally activated in many human cancers. Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide, but the molecular mechanisms of HCC are still poorly understood. Current studies indicate that Wnt/β-catenin signaling pathway plays a key role in the development and progression of HCC. Validating the role and mechanism of Wnt/β-catenin signaling pathway in HCC will provide a theoretical basis for early diagnosis and treatment of HCC. In this review, we summarize the role of Wnt/β-catenin signaling pathway in HCC and the progress of current researches.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Carcinoma, Hepatocellular
/
Wnt Proteins
/
Beta Catenin
/
Wnt Signaling Pathway
/
Carcinogenesis
/
Liver Neoplasms
Type of study:
Screening study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2014
Type:
Article
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