Preliminary investigation on the relation between clinical progress and anti-small monomolecular peptides antibody in individual infected with HIV / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 286-287, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-250532
ABSTRACT
<p><b>OBJECTIVE</b>To study the quantity of anti-R7V in individuals infected with HIV and AIDS patients and its relation with the progression of disease.</p><p><b>METHODS</b>ELISA and precipitation and other methods were used to investigate the quantity of anti-R7V in asymptomatic long-term survivors and AIDS patients.</p><p><b>RESULTS</b>Positive rate and quantity of anti-R7V were higher in the HIV active ones and AIDS. It showed that the quantity and positive rate of anti-R7V were rather high in dissolving test.</p><p><b>CONCLUSIONS</b>It is strong suggestion for anti-R7V to obstruct the replication of virus by interfering the connection between HIV with CCR5 or CXCR4 and so it impossible HIV entering to CD4+ T cells.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Blood
/
HIV Antibodies
/
HIV Infections
/
Follow-Up Studies
/
Acquired Immunodeficiency Syndrome
/
HIV-1
/
Receptors, CCR5
/
Receptors, CXCR4
/
HIV Long-Term Survivors
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2002
Type:
Article
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