Epidemiological feature of hepatitis B in Zaozhuang City, Shandong Province / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the prevalence and the epidemiological feature of hepatitis B in the population of Zaozhuang and the seroepidemiology of hepatitis B virus infection.</p><p><b>METHODS</b>HBsAg, anti-HBs and anti-HBc were detected in 963 sera collected from 312 families by RIA, which were selected by multistage and stratified cluster sampling.</p><p><b>RESULTS</b>The results indicated that the standardized positive rates of HBsAg, anti-HBs and anti-HBc were 7.08%, 37.56% and 41.35%, respectively and the standardized prevalence rate of hepatitis B virus infection was 44.37%. The positive rate of HBsAg was higher in male subjects and in the urban area groups than those in female subjects (P<0.05) and in rural area groups (P<0.01), respectively. There was no significant difference in the positive rate of HBsAg among all age groups and occupation groups (P>0.05). The positive rates of anti-HBs and anti-HBc and infective rate of hepatitis B virus increased with age. The infective rate of hepatitis B virus was higher in male subjects and in rural area groups than those in female subjects (P<0.05) and in urban area groups (P<0.05), respectively.</p><p><b>CONCLUSIONS</b>The HBV infective rate of population was higher in Zaozhuang city; measures of prevention and control should be taken actively and effectively.</p>