Simultaneous determination of 56 organochlorine and pyrethroid pesticides in traditional Chinese medicines by GC coupled with dual-tower and dual-column / 药学学报
Acta Pharmaceutica Sinica
;
(12): 353-358, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-250580
ABSTRACT
The paper is to report the establishment of a method for the determination of multi-residue organochlorine and pyrethroid pesticides in traditional Chinese medicines (TCMs). Fifty-six pesticides were extracted by high-speed homogenization, and then purified through gel permeation chromatography (GPC) and solid phase extraction (SPE) cartridges. The residues were simultaneously identified and quantified by GC-ECD equipped with dual tower, dual column and two micro-ECD detectors. The analytical performance was demonstrated by the analysis of 3 TCMs samples' extracts, spiked at three concentration levels for each pesticide. In general, the recoveries ranging from 70% to 110%, with relative standard deviations (RSDs) better than 15%, were obtained. The limit of detection (LOD) for most of the targeted pesticides tested was below 0.01 mg kg(-1). The method had good extraction efficiency, purification effect and good reproducibility, which could be applied to the determination of organochlorine and pyrethroid pesticide residues in the routine analysis of TCMs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pyrethrins
/
Drugs, Chinese Herbal
/
Pesticide Residues
/
Chemistry
/
Drug Contamination
/
Reproducibility of Results
/
Chromatography, Gas
/
Chromatography, Gel
/
Solid Phase Extraction
/
Limit of Detection
Type of study:
Prognostic study
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2010
Type:
Article
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