Advances in the study of the anti-tumor activity of small molecule vascular disrupting agents / 药学学报
Acta Pharmaceutica Sinica
;
(12): 283-288, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-250590
ABSTRACT
Vascular disrupting agents (VDAs) have presented a new kind of anti-cancer drug in recent years. VDAs take advantage of the weakness of established tumor endothelial cells and their supporting structures. In contrast to anti-angiogenic therapy, which inhibits the outgrowth of new blood vessels, vascular targeting treatments selectively attack the existing tumor vasculature. Here we summarized the anti-tumor activities, mechanisms and clinical applications of small molecule VDAs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligopeptides
/
Organophosphorus Compounds
/
Pathology
/
Pharmacology
/
Serine
/
Stilbenes
/
Bibenzyls
/
Molecular Structure
/
Chemistry
/
Diphosphates
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2010
Type:
Article
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