Advances in novel anti-HIV-1 drugs and drug candidates: 2005-2008

Pu-rong ZHENG; Hai XUE; Zhi-yan XIAO; Gang LIU

Advances in novel anti-HIV-1 drugs and drug candidates: 2005-2008 / 药学学报

Pu-rong ZHENG; Hai XUE; Zhi-yan XIAO; Gang LIU.

Acta Pharmaceutica Sinica ; (12): 154-164, 2010.

Article in Chinese | WPRIM | ID: wpr-250644

ABSTRACT

ABSTRACT

HIV and AIDS remain as the crucial global health concern, therefore, research and development of novel anti-HIV-1 chemical therapeutics is still of paramount significance, which may be illuminated by cases of successful marketed drugs. Herein, we document the discovery and biological profile of new anti-HIV-1 drugs approved by FDA between 2005 and 2008 and some drug candidates are also discussed.

Subject(s)

Humans; Acquired Immunodeficiency Syndrome; Drug Therapy; Anti-HIV Agents; Chemistry; Pharmacology; Therapeutic Uses; HIV Fusion Inhibitors; Chemistry; Pharmacology; Therapeutic Uses; HIV Infections; Drug Therapy; HIV Integrase Inhibitors; Chemistry; Pharmacology; Therapeutic Uses; HIV Protease Inhibitors; Chemistry; Pharmacology; Therapeutic Uses; HIV-1; Molecular Structure; Reverse Transcriptase Inhibitors; Chemistry; Pharmacology; Therapeutic Uses

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Molecular Structure / HIV Infections / Chemistry / Acquired Immunodeficiency Syndrome / HIV-1 / HIV Protease Inhibitors / Reverse Transcriptase Inhibitors / HIV Integrase Inhibitors / Anti-HIV Agents Limits: Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2010 Type: Article

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