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Effect of compatibilities and proportions of shuanglong formula on acute myocardial infarction in rats / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 3176-3179, 2011.
Article in Chinese | WPRIM | ID: wpr-251172
ABSTRACT
<p><b>OBJECTIVE</b>To verify the rational of Chinese medicine Shuanglong formula.</p><p><b>METHOD</b>Rat models of acute myocardial ischemia were induced by hydrochloride isoproterenol. ECG J point change, myocardial infarction area and cellular enzyme (CK, LDH, SOD and MDA) levels were observed and detected to show protective effect of treatment groups.</p><p><b>RESULT</b>The single drug prescriptions and compatibilities both could improve ECG performance, decrease levels of CK, LDH, SOD and MDA in serum, and reduce a certain myocardial infarct size.</p><p><b>CONCLUSION</b>The Shuanglong formula at the high dose of 37 was proved to be more effective on myocardial ischemia.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Drugs, Chinese Herbal / Rats, Sprague-Dawley / Disease Models, Animal / Drug Therapy / Electrocardiography / Isoproterenol / Myocardial Infarction Limits: Animals Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Drugs, Chinese Herbal / Rats, Sprague-Dawley / Disease Models, Animal / Drug Therapy / Electrocardiography / Isoproterenol / Myocardial Infarction Limits: Animals Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2011 Type: Article