Effect of compatibilities and proportions of shuanglong formula on acute myocardial infarction in rats / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3176-3179, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-251172
ABSTRACT
<p><b>OBJECTIVE</b>To verify the rational of Chinese medicine Shuanglong formula.</p><p><b>METHOD</b>Rat models of acute myocardial ischemia were induced by hydrochloride isoproterenol. ECG J point change, myocardial infarction area and cellular enzyme (CK, LDH, SOD and MDA) levels were observed and detected to show protective effect of treatment groups.</p><p><b>RESULT</b>The single drug prescriptions and compatibilities both could improve ECG performance, decrease levels of CK, LDH, SOD and MDA in serum, and reduce a certain myocardial infarct size.</p><p><b>CONCLUSION</b>The Shuanglong formula at the high dose of 37 was proved to be more effective on myocardial ischemia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Rats, Sprague-Dawley
/
Disease Models, Animal
/
Drug Therapy
/
Electrocardiography
/
Isoproterenol
/
Myocardial Infarction
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2011
Type:
Article
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