Chemical studies on alkaloids of Chinese medicinal herbs Daphniphyllum macropodum / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3134-3136, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-251181
ABSTRACT
<p><b>OBJECTIVE</b>To study the alkaloids of the Chinese medicinal herbs Daphniphyllum macropodum for in search for new bioactive substances.</p><p><b>METHOD</b>The CHCl3 extract of D. macropodum was subjected to repeated column chromatography on silica gel to afford four pure compounds (1-4). Their structures were determined on the basis of detailed spectroscopic analysis and comparison with the data reported in the literature.</p><p><b>RESULT</b>The four known compounds were isolated and elucidated as Daphniphyllum alkaloids with different carbon skeletons, namely longistylumphylline A (1), deoxycalyciphylline B (2), daphnicyclidin B (3) and H (4), respectively.</p><p><b>CONCLUSION</b>All compounds were isolated from the titled plant for the first time. The discovery of daphnicyclidin B (3) and H (4) further confirmed the biogenetic relationship between the two compounds and the previously reported macropodumines A-C, found in the same plant.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Chemistry
/
Magnoliopsida
/
Alkaloids
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2011
Type:
Article
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