Experimental study on preventive effect of Yougui drink on femoral head necrosis in rats under micro CT / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 1106-1110, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-251569
ABSTRACT
<p><b>OBJECTIVE</b>To explore the preventive effect of Yougui drink on femoral head necrosis in rats under micro CT.</p><p><b>METHODS</b>Twenty-five SD rats were divided into steroid hormone group (group A, 10 rats ), Yougui drink group (group B,10 rats) and normal group (group C,5 rats)with random number table. Endotoxin were injected into abdominal cavity of rats in group A and B for 2 days, methylprednisolone sodium succinate were injected by gluteus for twice a week continued for 6 weeks; group B were gavaged by Yougui drink (veryday for 8 weeks; group C did not do any processing. All rats were killed on the 10th weeks,m icro CT were used to scan femoral head in vitro and preventive effect of Yougui drink (n femoral head necrosis in rats.</p><p><b>RESULTS</b>There was statistical significance in BMD, BV/TV, Tb.N, Tb, Th, Thb, Sp, BS/TV and DA but no significance in SMI between group A and B. Comparison between A and C, there was significant meaning in BMD, BV/TV, Tb.N, Tb, Th, Tb, Sp, BS/TV, DA and SMI.</p><p><b>CONCLUSION</b>Yougui drink on femoral head necrosis in rats under micro CT has preventive effect from BMD BV/TV, Tb.N, Tb, Th, Tb, Sp, BS/TV and DA.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Diagnostic Imaging
/
Drugs, Chinese Herbal
/
Bone Density
/
Rats, Sprague-Dawley
/
Apoptosis
/
Therapeutic Uses
/
X-Ray Microtomography
/
Femur Head Necrosis
/
Methods
Type of study:
Diagnostic study
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2015
Type:
Article
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