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A Surgical Case of Lymphocytic Hypophysitis with Progressive Visual Worsening
Journal of Korean Neurosurgical Society ; : 216-219, 2007.
Article in English | WPRIM | ID: wpr-25258
ABSTRACT
Lymphocytic hypophysitis is a clinically rare disease, and it has been known to be an autoimmune disease which mainly affects pregnant women at the end of gestation or right after delivery. The authors experienced a case of lymphocytic hypophysitis in a 29-year-old pregnant woman with rapid progressing visual disturbance. Sella MRI showed a mass-like lesion of hypophysis and hypertrophy of pituitary stalk with evidences of hypopituitarism. Cesarean section was done and then TSA was performed. The pathologic diagnosis was lymphocytic hypophysitis. After TSA, visual acuity was improved and visual field defect was recovered. She was given thyroid hormone replacement therapy because of transient partial hypopituitarism for 6 months after surgery. One must consider the probability of lymphocytic hypophysitis, if there are alteration of visual acuity and visual field defect which aggravate rapidly during pregnancy due to mass effect, decreased serum hormonal levels shown in hypopituitarism and sella MRI findings of hypertrophy of pituitary stalk and enlargement of pituitary gland.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pituitary Gland / Pituitary Gland, Posterior / Autoimmune Diseases / Thyroid Gland / Magnetic Resonance Imaging / Visual Acuity / Visual Fields / Cesarean Section / Hormone Replacement Therapy / Rare Diseases Type of study: Diagnostic study Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Journal of Korean Neurosurgical Society Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pituitary Gland / Pituitary Gland, Posterior / Autoimmune Diseases / Thyroid Gland / Magnetic Resonance Imaging / Visual Acuity / Visual Fields / Cesarean Section / Hormone Replacement Therapy / Rare Diseases Type of study: Diagnostic study Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Journal of Korean Neurosurgical Society Year: 2007 Type: Article